Discontinued drugs in 2007: anti-infectives

被引：0
|
作者：
Ryder, Neil S. [1 ]
机构：
[1] Novartis Inst BioMed Res Inc, Infect Dis, Cambridge, MA 02139 USA
来源：
EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2009年 / 18卷 / 01期
关键词：
anti-infectives; discontinued drugs; HCV; herpes virus; HIV; vaccine; HEPATITIS-C VIRUS; POLYMERASE INHIBITORS; VACCINE; REPLICATION; RESISTANCE; RESPONSES; SELECTION; PROTEASE; TYPE-1; NO;
D O I：
10.1517/13543780802614920
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Twelve drugs related to therapy and/or prevention of infectious diseases were discontinued from development during 2007. All of these agents were aimed at viral infections, primarily hepatitis C virus (six agents) and HIV (five agents). Nearly half were vaccines, including three against HIV, a therapeutic vaccine for hepatitis C, and a vaccine for prevention and treatment of herpes simplex virus type 2. Each of these agents is briefly reviewed and the reasons for failure are discussed.
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页码：1 / 11
页数：11
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