Iridium-Catalyzed Decarboxylative N-Alkylation of α-Amino Acids with Primary Alcohols

被引：6
|
作者：
Wu, Jiashou [1 ,2 ]
Jiang, Huajiang [1 ]
Chen, Dingben [1 ]
Shen, Jianfen [1 ]
Zhao, Datong [2 ]
Xiang, Jing [3 ]
Zhou, Qizhong [1 ]
机构：
[1] Taizhou Univ, Sch Pharmaceut & Chem Engn, Taizhou 318000, Zhejiang, Peoples R China
[2] Zhejiang Hisoar Pharmaceut Co LTD, Taizhou 318000, Zhejiang, Peoples R China
[3] Yangtze Univ, Coll Chem & Environm Engn, Jinzhou 434020, Hubei, Peoples R China
来源：
SYNLETT | 2014年 / 25卷 / 04期
关键词：
iridium; amine; decarboxylative N-alkylation; amino acid; alcohol; AZOMETHINE YLIDES;
D O I：
10.1055/s-0033-1340474
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new decarboxylative N-alkylation reaction of -amino acids has been developed. A variety of tertiary amines were obtained in good to excellent yields via the decarboxylative N-alkylation reaction of -amino acids with primary alcohols catalyzed by a Cp*Ir complex.
引用
收藏
页码：539 / 542
页数：4
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