De novo AML with trilineage myelodysplasia and a novel t(11;12)(p15;q13)

被引：11
|
作者：
Wong, KF [1 ]
Kwong, YL [1 ]
So, CC [1 ]
机构：
[1] QUEEN MARY HOSP,DEPT MED,HONG KONG,HONG KONG
来源：
CANCER GENETICS AND CYTOGENETICS | 1998年 / 100卷 / 01期
关键词：
D O I：
10.1016/S0165-4608(97)00007-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
De novo acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) is an uncommon form of leukemia characterized by a dyshematopoietic picture accompanying the acute leukemia, a poor response to induction chemotherapy, and a tendency to relapse with pure myelodysplastic syndrome. Cytogenetic information on this entity is scarce, although some cases have been reported to be associated with t(7;11)(p15;p15). A 41-year-old woman who had a history of radiotherapy for breast cancer presented with AML/TMDS and was found to have a unique t(11;12)(p15;q13) abnormality. (C) Elsevier Science Inc., 1998.
引用
收藏
页码：49 / 51
页数：3
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