Bicyclic furano-, pyrrolo-, and thiopheno[2,3-d] derivatives of pyrimidine nucleosides: Synthesis and antiviral properties

被引：6

作者：

Ivanov, M. A. ^{[1
]}

Aleksandrova, L. A. ^{[1
]}

机构：

[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 119991, Russia

来源：

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2013年 / 39卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

nucleosides; furano-, thiopheno-, and pyrrolo[2,3-d]pyrimidine nucleosides; alkynes; 5 '-O-triphosphates of nucleosides; varicella zoster; hepatitis C virus; bovine viral diarrhea virus; RNA polymerase of hepatitis C virus; NTPase/helicase of hepatitis C virus; VARICELLA-ZOSTER-VIRUS; HEPATITIS-C VIRUS; L-ASCORBIC-ACID; PALLADIUM CATALYZED SYNTHESIS; 2,3-DIDEHYDRO-2,3-DIDEOXYADENOSINE D4A; SELECTIVE INHIBITORS; SUBSTITUTED FURANS; POTENT INHIBITORS; ANALOGS BCNAS; VZV;

D O I：

10.1134/S1068162013010044

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The methods of synthesis of furano-, thiopheno-, and pyrrolo[2,3-d]pyrimidine deoxyribonucleosides and their derivatives and studies of the relationship between the structure and the antiviral activity of these compounds towards the viruses of varicella zoster, hepatitis C, and others have been reviewed.

引用

页码：22 / 39

页数：18

共 50 条

[1] Bicyclic furano-, pyrrolo-, and thiopheno[2,3-d] derivatives of pyrimidine nucleosides: Synthesis and antiviral properties
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[2] Novel 5′-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides
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