A simple pyrazoline-based fluorescent probe for Zn2+ in aqueous solution and imaging in living neuron cells

被引：39
|
作者：
Zhang, Ting-Ting [1 ]
Wang, Fang-Wu [2 ]
Li, Meng-Meng [1 ]
Liu, Jin-Ting [1 ]
Miao, Jun-Ying [2 ]
Zhao, Bao-Xiang [1 ]
机构：
[1] Shandong Univ, Sch Chem & Chem Engn, Inst Organ Chem, Jinan 250100, Peoples R China
[2] Shandong Univ, Sch Life Sci, Inst Dev Biol, Jinan 250100, Peoples R China
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2013年 / 186卷
基金：
中国国家自然科学基金;
关键词：
Pyrazoline; Fluorescent probe; Zinc ion; Cell imaging; SH-SY5Y cells; TURN-ON; ZINC IONS; SENSOR; CHEMOSENSOR; WATER; CYTOTOXICITY; FLUOROPHORE; PHYSIOLOGY; BEHAVIOR; BIOLOGY;
D O I：
10.1016/j.snb.2013.06.085
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple pyrazoline-based highly sensitive fluorescent probe for Zn2+ in aqueous solution and biological Zn2+ detection has been developed. The probe displays a good selective fluorescence enhancement (13-fold) for Zn2+ over various metal ions. The new probe is cell-permeable and can be successfully used to image intracellular Zn2+ in living neuron cells. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：755 / 760
页数：6
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