Posterior circulation ischaemic stroke and transient ischaemic attack: diagnosis, investigation, and secondary prevention

被引:148
|
作者
Markus, Hugh S. [1 ]
van der Worp, H. Bart [2 ]
Rothwell, Peter M. [3 ]
机构
[1] Univ Cambridge, Cambridge CB2 2QQ, England
[2] Univ Med Ctr Utrecht, Brain Ctr Rudolf Magnus, Dept Neurol & Neurosurg, Utrecht, Netherlands
[3] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford, England
来源
LANCET NEUROLOGY | 2013年 / 12卷 / 10期
基金
英国惠康基金;
关键词
VERTEBRAL ARTERY-STENOSIS; NATURAL-HISTORY; RECURRENT STROKE; POOLED DATA; INFARCTION; PROGNOSIS; MANAGEMENT; THERAPY; RISK; ENDARTERECTOMY;
D O I
10.1016/S1474-4422(13)70211-4
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A fifth of all strokes and transient ischaemic attacks occur in the posterior circulation arterial territory. Diagnosis can be challenging, in part because of substantial overlap in symptoms and signs with ischaemia in the anterior circulation. Improved methods of non-invasive imaging of the vertebrobasilar arterial tree have been used in recent prospective follow-up studies, which have shown a high risk of early recurrent stroke, particularly when there is associated vertebrobasilar stenosis. This finding emphasises the importance of urgent secondary prevention, and the role of stenting for vertebral stenosis is being investigated.
引用
收藏
页码:989 / 998
页数:10
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