Verification of the grid size and angular increment effects in lung stereotactic body radiation therapy using the dynamic conformal arc technique

被引:0
|
作者
Park, Hae-Jin [1 ,2 ,3 ]
Park, Ji-Yeon [1 ,2 ]
Suh, Tae-Suk [1 ,2 ]
Lee, Jeong-Woo [4 ]
Kim, Mi-Hwa [3 ]
Oh, Young-Taek [3 ]
Chun, Mison [3 ]
Noh, O. Kyu [3 ]
Suh, Susie [5 ,6 ]
机构
[1] Catholic Univ Korea, Dept Biomed Engn, Coll Med, Seoul 137701, South Korea
[2] Catholic Univ Korea, Res Inst Biomed Engn, Coll Med, Seoul 137701, South Korea
[3] Ajou Univ, Sch Med, Dept Radiat Oncol, Suwon 443721, South Korea
[4] Konkuk Univ, Dept Radiat Oncol, Med Ctr, Seoul 143729, South Korea
[5] Stanford Univ, Sch Med, Dept Pediat Radiol Microbiol & Immunol, Stanford, CA 94305 USA
[6] Stanford Univ, Sch Med, Mol Imaging Program Stanford, Stanford, CA 94305 USA
基金
新加坡国家研究基金会;
关键词
Dynamic conformal arc therapy (DACT); Grid size; Angular increment; Film dosimetry;
D O I
10.3938/jkps.62.1672
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The dosimetric effects of variable grid size and angular increment were systematically evaluated in the measured dose distributions of dynamic conformal arc therapy (DCAT) for lung stereotactic body radiation therapy (SBRT). Dose variations with different grid sizes (2, 3, and 4 mm) and angular increments (2, 4, 6, and 10A degrees) for spherical planning target volumes (PTVs) were verified in a thorax phantom by using EBT2 films. Although the doses for identical PTVs were predicted for the different grid sizes, the dose discrepancy was evaluated using one measured dose distribution with the gamma tool because the beam was delivered in the same set-up for DCAT. The dosimetric effect of the angular increment was verified by comparing the measured dose area histograms of organs at risk (OARs) at each angular increment. When the difference in the OAR doses is higher than the uncertainty of the film dosimetry, the error is regarded as the angular increment effect in discretely calculated doses. In the results, even when a 2-mm grid size was used with an elaborate dose calculation, 4-mm grid size led to a higher gamma pass ratio due to underdosage, a steep-dose descent gradient, and lower estimated PTV doses caused by the smoothing effect in the calculated dose distribution. An undulating dose distribution and a difference in the maximum contralateral lung dose of up to 14% were observed in dose calculation using a 10A degrees angular increment. The DCAT can be effectively applied for an approximately spherical PTV in a relatively uniform geometry, which is less affected by inhomogeneous materials and differences in the beam path length.
引用
收藏
页码:1672 / 1677
页数:6
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