Polymer-wrapped single-walled carbon nanotubes: a transformation toward better applications in healthcare

被引：20
|
作者：
Chik, Mazzura Wan [1 ]
Hussain, Zahid [1 ]
Zulkefeli, Mohd [2 ]
Tripathy, Minaketan [1 ,3 ]
Kumar, Sunil [4 ]
Majeed, Abu Bakar Abdul [3 ]
Byrappa, K. [5 ]
机构：
[1] Univ Teknol MARA UiTM, Fac Pharm, Lab Fundamental Pharmaceut, Bandar Puncak Alam 42300, Selangor, Malaysia
[2] Int Med Univ, Dept Pharmaceut Chem, Sch Pharm, Kuala Lumpur 57000, Malaysia
[3] Univ Teknol MARA UiTM, Fac Pharm, Pharmaceut Life Sci Dept, Bandar Puncak Alam 42300, Selangor, Malaysia
[4] ICAR NBAIM, Kushmaur 275103, India
[5] Mangalore Univ, Mangalore 574199, Karnataka, India
来源：
DRUG DELIVERY AND TRANSLATIONAL RESEARCH | 2019年 / 9卷 / 02期
关键词：
Carbon nanotubes; Single-wall carbon nanotubes; Superhydrophobicity; Polymer wrapping; Solubility enhancers; Targeted drug delivery; SOLUTE SOLVENT INTERACTIONS; NONCOVALENT FUNCTIONALIZATION; BACTERIAL CYTOTOXICITY; DIAMETER CONTROL; PVP-SWNTS; DISPERSION; WATER; DELIVERY; SOLUBILIZATION; NANOPARTICLES;
D O I：
10.1007/s13346-018-0505-9
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
Carbon nanotubes (CNTs) possess outstanding properties that could be useful in several technological, drug delivery, and diagnostic applications. However, their unique physical and chemical properties are hindered due to their poor solubility. This article review's the different ways and means of solubility enhancement of single-wall carbon nanotubes (SWNTs). The advantages of SWNTs over the multi-walled carbon nanotubes (MWNTs) and the method of non-covalent modification for solubility enhancement has been the key interest in this review. The review also highlights a few examples of dispersant design. The review includes some interesting utility of SWNTs being wrapped with polymer especially in biological media that could mediate proper drug delivery to target cells. Further, the use of wrapped SWNTs with phospholipids, nucleic acid, and amphiphillic polymers as biosensors is of research interest. The review aims at summarizing the developments relating to wrapped SWNTs to generate further research prospects in healthcare.
引用
收藏
页码：578 / 594
页数：17
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