Cigarette smoking and its association with serum lipid/lipoprotein among Chinese nonagenarians/centenarians

被引:20
|
作者
Zhang Yan-Ling [1 ]
Zhao Dong-Qing [1 ]
Huang Chang-Quan [1 ]
Dong Bi-Rong [1 ]
机构
[1] Sichuan Univ, W China Hosp, Dept Geriatr, Chengdu 610041, Sichuang Provin, Peoples R China
来源
关键词
Serum lipid/lipoprotein; Cigarette smoking; Nonagenarians/Centenarians; DENSITY-LIPOPROTEIN-CHOLESTEROL; CARDIOVASCULAR-DISEASE; COGNITIVE IMPAIRMENT; RISK; DYSLIPIDEMIA; MORTALITY; OBESITY; CENTENARIANS; CESSATION; DEMENTIA;
D O I
10.1186/1476-511X-11-94
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Objective: Cigarette smoking had been confirmed as an increased risk for dyslipidemia, but none of the evidence was from long-lived population. In present study, we detected relationship between cigarette smoking habits and serum lipid/lipoprotein (serum Triglyceride (TG), Total cholesterol (TC), Low-density lipoprotein (LDL) and high-density lipoprotein (HDL)) among Chinese Nonagenarians/Centenarian. Methods: The present study analyzed data from the survey that was conducted on all residents aged 90 years or more in a district, there were 2,311,709 inhabitants in 2005. Unpaired Student's t test, X-2 test, and multiple logistic regression were used to analyze datas. Results: The individuals included in the statistical analysis were 216 men and 445 women. Current smokers had lower level of TC (4.05 +/- 0.81 vs. 4.21 +/- 0.87, t = 2.403, P = 0.017) and lower prevalence of hypercholesteremia (9.62% vs. 15.13%, X-2 = 3.018, P = 0.049) than nonsmokers. Unadjusted and adjusted multiple logistic regressions showed that cigarette smoking was not associated with risk for abnormal serum lipid/lipoprotein. Conclusions: In summary, we found that among Chinese nonagenarians/centenarians, cigarette smoking habits were not associated with increased risk for dyslipidemia, which was different from the association of smoking habits with dyslipidemia in general population.
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页数:6
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