Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by hydroxyapatite-column chromatography

被引：0
|
作者：
Xia, Zhidao [1 ]
Duan, Xuchen [1 ]
Locklin, Rachel M. [1 ]
Quijano, Mike [2 ]
Dobson, Roy L. M. [2 ]
Triffitt, James T. [1 ]
Ebetino, Frank H. [2 ]
Graham, R.
Russell, G. [1 ]
机构：
[1] Univ Oxford, Nuffield Dept Orthopaed Surg, Inst Musculoskeletal Sci, Oxford, England
[2] Procter & Gamble Pharmaceut, New Drug Dev, Mason, OH USA
来源：
BONE | 2008年 / 43卷
关键词：
D O I：
10.1016/j.bone.2008.07.126
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：S92 / S92
页数：1
相关论文
共 9 条
  • [1] Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by using hydroxyapatite-column chromatography and adsorption isotherms combined with mass spectrometric analysis
    Xia, Zhidao
    Duan, Xuchen
    Locklin, Rachel M.
    Quijano, Mike
    Dobson, Roy L. M.
    Triffitt, James T.
    Ebetino, Frank H.
    Russell, Graham R. G.
    BONE, 2008, 42 : S90 - S91
  • [2] Determination of the relative bone mineral-binding affinities of bisphosphonates by using hydroxyapatite-column chromatography combined with mass spectrometric analysis
    Duan, Xuchen
    Xia, Zhidao
    Zhang, Hao
    Quijano, Mike
    Dobson, Roy
    Barnett, Bobby
    Triffitt, James
    Dunford, James
    Ebetino, Frank
    Russell, R. Graham
    BONE, 2010, 46 : S23 - S23
  • [3] Refinements in the use of column chromatography to expose differences in relative binding affinities of bisphosphonates to hydroxyapatite
    不详
    CALCIFIED TISSUE INTERNATIONAL, 2006, 78 : S79 - S79
  • [4] Refining the use of hydroxyapatite column chromatography to reveal differences in relative binding affinities of bisphosphonates
    Lawson, MA
    Xia, Z
    Triffitt, JT
    Ebetino, FH
    Phipps, RJ
    Russell, RGG
    BONE, 2006, 38 (03) : S55 - S55
  • [5] The use of hydroxyapatite column chromatography as a novel method to reveal differences in relative binding affinities of bisphosphonates
    Lawson, MA
    Triffitt, JT
    Ebetino, FH
    Phipps, RJ
    White, DJ
    Russell, RGG
    BONE, 2005, 36 : S308 - S309
  • [6] A novel method to characterize relative mineral binding affinities of bisphosphonates and the structural requirements for binding by using ceramic hydroxyapatite column chromatography.
    Xia, Z.
    Lawson, M. A.
    Triffitt, J. T.
    Ebetino, F. H.
    McKenna, C. E.
    Marma, M.
    Kashemirov, B.
    Russell, R. G. G.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 : S191 - S191
  • [7] Potential bone mineral binding differences among bisphosphonates can be demonstrated by the use of hydroxyapatite column chromatography.
    Lawson, MA
    Triffitt, JT
    Ebetino, FH
    Barnett, BL
    Phipps, RJ
    Locklin, RM
    Russell, RGG
    JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (09) : S396 - S396
  • [8] Differences in the potential binding of phosphate containing compounds to bone mineral are revealed by the novel use of hydroxyapatite column chromatography
    Lawson, MA
    Triffitt, JT
    Ebetino, FH
    Barnett, BL
    Phipps, RJ
    White, DJ
    Russell, RGG
    JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (07) : 1303 - 1303
  • [9] Analysis of mineral binding activities of bisphosphonates by using hydroxyapatite chromatography and adsorption isotherms together with detection by light absorption, fluorescence derivatisation and tandem mass spectrometry
    Xia, Z.
    Duan, X.
    Locklin, R. M.
    Quijiano, M.
    Dobson, R. L. M.
    Triffitt, J. T.
    Ebetino, F. H.
    Russell, R. G.
    CALCIFIED TISSUE INTERNATIONAL, 2008, 82 : S254 - S254
1