Relationship between body mass index and incidence of breast cancer

Objective: To investigate the relationship between body mass index (BMI) and the breast cancer incidence, so as to making contribution to breast cancer screening in high-risk groups, to adjustment from passive medical treatment to active treatment Methods: BMI status of 206 breast cancer patients and that of 210 healthy subjects at different ages were compared and analyzed. Results: The mean BMI was significantly higher in breast cancer patients than in healthy subjects 24.45 +/- 3.50 vs. 23.80 +/- 3.10 kg/m(2), t=-2.189, P=0.001. When stratified by age, BMI were significantly higher in >= 60 age for breast cancer than that of control group (Z=-3.408, P=0.001) and no significant difference in <60 years old. Logistic regression analysis showed that BMI was a risk factor of breast cancer (OR=1.886, 95% CI: 1.122-3.009). Conclusion: BMI have a relationship with the occurrence of breast cancer, especially for >= 60 years old.