Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment

被引：19

作者：

Ponomarenko, V. I. ^{[1
,2
]}

Prokhorov, M. D. ^{[1
]}

Karavaev, A. S. ^{[1
,2
]}

Kiselev, A. R. ^{[3
]}

Gridnev, V. I. ^{[3
]}

Bezruchko, B. P. ^{[1
,2
]}

机构：

[1] Russian Acad Sci, Saratov Branch, Inst Radio Engn & Elect, Saratov, Russia

[2] Saratov NG Chernyshevskii State Univ, Dept Nano & Biomed Technol, Saratov, Russia

[3] Saratov Res Inst Cardiol, Saratov, Russia

来源：

EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS | 2013年 / 222卷 / 10期

基金：

俄罗斯基础研究基金会;

关键词：

BLOOD-PRESSURE; RR-INTERVAL; VARIABILITY; FLUCTUATIONS; RHYTHMS;

D O I：

10.1140/epjst/e2013-02048-1

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.

引用

页码：2687 / 2696

页数：10

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