Boric acid catalysed synthesis of α-aminonitriles by a three-component reaction at room temperature

被引:6
|
作者
Karimi-Jaberi, Zahed [1 ]
Bahrani, Abdolaziz [1 ]
机构
[1] Islamic Azad Univ, Firoozabad Branch, Dept Chem, Fars, Iran
关键词
alpha-aminonitriles; boric acid; trimethylsilyl cyanide; solvent-free conditions; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; RAPID SYNTHESIS; STRECKER REACTION; EFFICIENT; WATER;
D O I
10.3184/174751912X13352842814921
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple, efficient, and cost-effective method has been developed for the one-pot, three-component condensation reaction of trimethylsilyl cyanide, aldehydes and aromatic amines using boric acid as a heterogeneous solid acid catalyst, under solvent-free conditions. alpha-Aminonitriles were synthesised relatively quickly in good yields at room temperature.
引用
收藏
页码:326 / +
页数:2
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