The influence of spinning variables on the migration parameters in compact and ring-spun cotton yarns has been studied. Spinning variables include twist factor, twisting speed and spinning draft. Spinning mode is found to be the key factor in determining yarn structural responses. When compared with conventional ring-spun yarns, compact yarns have significantly smaller mean fibre position, helix angle and helix diameter, but display higher values of mean migration intensity, equivalent migration frequency and migration factor. Of the various spinning variables, twist factor and spindle speed significantly affect mean migration intensity, migration frequency and migration factor, whereas spinning draft affects each of these parameters in non-distinguishable manner.