Primary care veterinary usage of systemic glucocorticoids in cats and dogs in three UK practices
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作者:
O'Neill, D.
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Univ London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, EnglandUniv London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, England
O'Neill, D.
[1
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Hendricks, A.
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Univ London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, EnglandUniv London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, England
Hendricks, A.
[1
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Summers, J.
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机构:Univ London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, England
Summers, J.
Brodbelt, D.
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机构:Univ London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, England
Brodbelt, D.
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[1] Univ London Royal Vet Coll, Small Anim Med & Surg Grp, Hatfield AL9 7TA, Herts, England
OBJECTIVES: To describe systemic glucocorticoid usage in cats and dogs by three primary care veterinary practices in England and to ascertain risk factors for clinical use. To evaluate consistency of prescribing patterns across clinics. To validate a merged database of primary veterinary clinical data as a functional tool for clinical epidemiological research. METHODS: A merged database was established from clinical data on 31,273 cat and dog consultations with pharmacotherapy from three veterinary practices in England. Descriptive statistics described systemic glucocorticoid drug use in cats and dogs while mixed-effects logistic regression modelling evaluated risk factors. Individual clinic usage was compared. RESULTS: Overall, 1877 (16.68%) cat consultations and 2913 (14.55%) dog consultations resulted in systemic glucocorticoid therapy. Cats received higher parenteral (P<0.0001) and oral (P<0.0001) dose levels than dogs. Pathophysiological indication, age, skin condition, sex and clinic attended were significant risk factors for glucocorticoid prescription. Clinics varied widely in their odds of systemic glucocorticoid usage (P<0.0001). CLINICAL SIGNIFICANCE: An evidence base for systemic glucocorticoid prescribing by primary care small animal practices in England is provided. Clinic attended was a significant risk factor, indicating wide variation in prescribing patterns between clinics. A merged primary care veterinary clinical database was effective for epidemiological research.
机构:
Univ London, Royal Vet Coll, Pathobiol & Populat Hlth, London, EnglandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Elkholly, Doaa A.
Brodbelt, Dave C.
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Univ London, Royal Vet Coll, Pathobiol & Populat Hlth, London, EnglandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Brodbelt, Dave C.
Church, David B.
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Univ London, Royal Vet Coll, Clin Sci & Serv, London, EnglandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Church, David B.
Pelligand, Ludo
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Univ London, Royal Vet Coll, Clin Sci & Serv, London, England
Univ London, Royal Vet Coll, Comparat Biomed Sci, London, EnglandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Pelligand, Ludo
Mwacalimba, Kennedy
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Zoetis, Outcomes Res, Parsippany, NJ USAUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Mwacalimba, Kennedy
Wright, Andrea K.
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Zoetis, Outcomes Res, Dublin, IrelandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
Wright, Andrea K.
O'Neill, Dan G.
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Univ London, Royal Vet Coll, Pathobiol & Populat Hlth, London, EnglandUniv London, Royal Vet Coll, Pathobiol & Populat Hlth, London, England
机构:
Tufts Univ, Cummings Sch Vet Med, North Grafton, MA USATufts Univ, Cummings Sch Vet Med, North Grafton, MA USA
Smith, Alison
Wayne, Annie S.
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Tufts Univ, Cummings Sch Vet Med, Dept Clin Sci, 200 Westboro Rd, North Grafton, MA 01536 USATufts Univ, Cummings Sch Vet Med, North Grafton, MA USA
Wayne, Annie S.
Fellman, Claire L.
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Tufts Univ, Cummings Sch Vet Med, Dept Clin Sci, 200 Westboro Rd, North Grafton, MA 01536 USATufts Univ, Cummings Sch Vet Med, North Grafton, MA USA
Fellman, Claire L.
Rosenbaum, Marieke H.
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Tufts Univ, Cummings Sch Vet Med, Dept Infect Dis & Global Hlth, North Grafton, MA USATufts Univ, Cummings Sch Vet Med, North Grafton, MA USA