Vulvovaginal Pyoderma Gangrenosum in a Patient Treated With Ocrelizumab for Multiple Sclerosis

被引：2

作者：

Breneman, Alyssa N. ^{[1
]}

Eber, Ariel E. ^{[2
]}

Haque, Hoosna ^{[3
]}

Levine, Libby ^{[4
,5
]}

Askanase, Anca ^{[6
]}

Riley, Claire S. ^{[4
,5
]}

Pomeranz, Miriam Keltz ^{[7
]}

Hassan, Dahlia ^{[6
]}

Mancebo, Silvia E. ^{[8
]}

Polin, Melanie ^{[9
]}

Melamed, Alexander ^{[10
]}

Bordone, Lindsey A. ^{[2
]}

Rosser, Mary ^{[3
]}

Gockley, Allison ^{[10
]}

Gallitano, Stephanie M. ^{[2
]}

机构：

[1] Columbia Univ, Vagelos Coll Phys & Surg, 161 Ft Washington Ave,12th Flr, New York, NY 10032 USA

[2] Columbia Univ, Dept Dermatol, Irving Med Ctr, New York, NY 10032 USA

[3] Columbia Univ, Dept Obstet & Gynecol, Div Gynecol, Vagelos Coll Phys & Surg, New York, NY 10032 USA

[4] Columbia Univ, Dept Neurol, Irving Med Ctr, New York, NY 10032 USA

[5] Columbia Univ, Multiple Sclerosis Ctr, Irving Med Ctr, New York, NY 10032 USA

[6] Columbia Univ, Dept Rheumatol, Irving Med Ctr, New York, NY 10032 USA

[7] NYU, Ronald O Perelman Dept Dermatol, Sch Med, New York, NY USA

[8] Cornell Univ, Dept Dermatol, Weill Med Coll, New York, NY 10021 USA

[9] Columbia Univ, Dept Obstet & Gynecol, Vagelos Coll Phys & Surg, New York, NY 10032 USA

[10] Columbia Univ, Dept Obstet & Gynecol, Div Gynecol Oncol, Vagelos Coll Phys & Surg, New York, NY 10032 USA

来源：

JOURNAL OF LOWER GENITAL TRACT DISEASE | 2022年 / 26卷 / 02期

关键词：

pyoderma gangrenosum; vulvovaginal; rituximab; ocrelizumab; intravenous immunoglobulin; side effect;

D O I：

10.1097/LGT.0000000000000661

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ocrelizumab is an anti-CD20 monoclonal antibody treatment for multiple sclerosis (MS).1 Pyoderma gangrenosum (PG) is an inflammatory, ulcerative dermatosis.2 Vulvovaginal PG has rarely been associated with rituximab, another anti-CD20 monoclonal antibody.2 We report a unique case of ocrelizumab-associated vulvovaginal PG. Copyright © 2022 ASCCP.

引用

页码：189 / 191

页数：3

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