Genetic characterization of canine influenza A virus (H3N2) in Thailand

被引:61
|
作者
Bunpapong, Napawan [1 ]
Nonthabenjawan, Nutthawan [1 ,2 ]
Chaiwong, Supassama [1 ,2 ]
Tangwangvivat, Ratanaporn [1 ,2 ]
Boonyapisitsopa, Supanat [1 ]
Jairak, Waleemas [1 ,2 ]
Tuanudom, Ranida [1 ]
Prakairungnamthip, Duangduean [1 ,3 ]
Suradhat, Sanipa [1 ,3 ]
Thanawongnuwech, Roongroje [1 ,4 ]
Amonsin, Alongkorn [1 ,2 ]
机构
[1] Chulalongkorn Univ, Fac Vet Sci, Ctr Excellence Emerging & Reemerging Infect Dis, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Dept Vet Publ Hlth, Fac Vet Sci, Bangkok 10330, Thailand
[3] Chulalongkorn Univ, Dept Vet Microbiol, Fac Vet Sci, Bangkok 10330, Thailand
[4] Chulalongkorn Univ, Dept Vet Pathol, Fac Vet Sci, Bangkok 10330, Thailand
关键词
Canine influenza; H3N2; Genetic characterization; Thailand; REVERSE-TRANSCRIPTASE PCR; ANTIGENIC SITES; PANDEMIC H1N1; HEMAGGLUTININ; DOGS; TRANSMISSION; H5N1; INFECTION; LENGTH; ASSAY;
D O I
10.1007/s11262-013-0978-z
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
In January 2012, several clinical cases of dogs with flu-like symptoms, including coughing, sneezing, nasal discharge, and fever, were reported in a small-animal hospital located in Bangkok, Thailand. One influenza A virus was identified and characterized as an avian-like influenza virus H3N2. The virus was named A/canine/Thailand/CU-DC5299/12. A phylogenetic analysis indicated that the canine virus belonged to an avian Eurasian lineage and was genetically related to the canine influenza viruses H3N2 from China and Korea. This canine virus displays a unique genetic signature with two amino acid insertions in the NA protein, which is similar to the canine influenza viruses from eastern China (Zhejiang and Jiangsu). This study constitutes the first report of H3N2 canine influenza virus infection in a small-animal hospital in Thailand.
引用
收藏
页码:56 / 63
页数:8
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