THE POSITIVE PREDICTIVE VALUE OF LYME ELISA FOR THE DIAGNOSIS OF LYME DISEASE IN CHILDREN

被引：11
|
作者：
Lipsett, Susan C. [1 ]
Pollock, Nira R. [2 ,3 ]
Branda, John A. [4 ]
Gordon, Caroline D. [1 ]
Gordon, Catherine R. [1 ]
Lantos, Paul M. [5 ,6 ]
Nigrovic, Lise E. [1 ]
机构：
[1] Boston Childrens Hosp, Div Emergency Med, Boston, MA 02115 USA
[2] Boston Childrens Hosp, Infect Dis Diagnost Lab, Boston, MA 02115 USA
[3] Beth Israel Deaconess Med Ctr, Div Infect Dis, Boston, MA 02215 USA
[4] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA
[5] Duke Univ, Sch Med, Div Pediat Infect Dis, Durham, NC USA
[6] Duke Univ, Sch Med, Div Pediat Infect Dis, Durham, NC USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2015年 / 34卷 / 11期
基金：
美国国家卫生研究院;
关键词：
Lyme disease; Lyme ELISA; predictive value; pediatrics; KNEE MONOARTHRITIS; MENINGITIS; VALIDATION; MODEL;
D O I：
10.1097/INF.0000000000000858
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA index values 3.0 had a positive predictive value of 99.4% (95% confidence interval: 98.1-99.8%) for Lyme disease, making a supplemental Western immunoblot potentially unnecessary.
引用
收藏
页码：1260 / 1262
页数：3
相关论文
共 50 条
  • [1] Multicenter Evaluation of the C6 Lyme ELISA Kit for the Diagnosis of Lyme Disease
    Zannoli, Silvia
    Fantini, Michela
    Semprini, Simona
    Marchini, Barbara
    Ceccarelli, Barbara
    Sparacino, Monica
    Schiavone, Pasqua
    Belgrano, Anna
    Ruscio, Maurizio
    Gobbetti, Martina
    Nicoletti, Maira
    Robatscher, Eva
    Pagani, Elisabetta
    Sambri, Vittorio
    [J]. MICROORGANISMS, 2020, 8 (03)
  • [2] DIAGNOSIS OF LYME-DISEASE IN CHILDREN
    GERBER, MA
    SHAPIRO, ED
    [J]. JOURNAL OF PEDIATRICS, 1992, 121 (01): : 157 - 162
  • [3] Diagnosis and treatment of Lyme disease in children
    Bahadori, Atessa
    Ritz, Nicole
    Zimmermann, Petra
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 2023, 108 (06): : 422 - 428
  • [4] Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence
    Lantos, Paul M.
    Branda, John A.
    Boggan, Joel C.
    Chudgar, Saumil M.
    Wilson, Elizabeth A.
    Ruffin, Felicia
    Fowler, Vance
    Auwaerter, Paul G.
    Nigrovic, Lise E.
    [J]. CLINICAL INFECTIOUS DISEASES, 2015, 61 (09) : 1374 - 1380
  • [5] Diagnosis, Treatment, and Prevention of Lyme Disease in Children
    Stephen C. Eppes
    [J]. Pediatric Drugs, 2003, 5 (6) : 363 - 372
  • [6] Racial Differences in the Diagnosis of Lyme Disease in Children
    Hunt, Kathryn M.
    Michelson, Kenneth A.
    Balamuth, Fran
    Thompson, Amy D.
    Levas, Michael N.
    Neville, Desiree N.
    Kharbanda, Anupam B.
    Chapman, Laura
    Nigrovic, Lise E.
    [J]. CLINICAL INFECTIOUS DISEASES, 2023, 76 (06) : 1129 - 1131
  • [7] Diagnosis of Lyme Disease
    Pitrak, David
    Nguyen, Cynthia T.
    Cifu, Adam S.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2022, 327 (07): : 676 - 677
  • [8] Diagnosis of Lyme disease
    Depietropaolo, DL
    Powers, JH
    Gill, JM
    Foy, AJ
    [J]. AMERICAN FAMILY PHYSICIAN, 2005, 72 (02) : 297 - 304
  • [9] Lyme disease in children
    LeibFeldman, B
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (15): : 1107 - 1107
  • [10] Lyme disease in children
    Shapiro, ED
    Seltzer, EG
    [J]. SEMINARS IN NEUROLOGY, 1997, 17 (01) : 39 - 44
12345