Intravenous immunoglobulin for immunomodulation of systemic lupus erythematosus

被引：32
|
作者：
Sherer, Y
Shoenfeld, Y [1 ]
机构：
[1] Tel Aviv Univ, Dept Med B, Sackler Fac Med, Chaim Sheba Med Ctr, IL-52621 Tel Hashomer, Israel
[2] Tel Aviv Univ, Ctr Autoimmune Dis, Sackler Fac Med, Chaim Sheba Med Ctr, IL-52621 Tel Hashomer, Israel
来源：
AUTOIMMUNITY REVIEWS | 2006年 / 5卷 / 02期
关键词：
systemic lupus erythematosus; intravenous immunoglobulin; immunomodulation;
D O I：
10.1016/j.autrev.2005.09.002
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Intravenous immunoglobulin (IVIg) is used for replacement therapy in immunodeficiency states and for immunomodulation of various autoimmune diseases. Several case reports and series support a beneficial role of IVlg in systemic lupus erythematosus (SLE), both as salvage immunotherapy and in control of disease activity in general and amelioration of classical disease manifestations. Further, lupus nephritis can also be treated usually successfully with IVIg. A few questions remain unanswered as to the appropriate therapeutic dosage and the clinical manifestations that can be best treated with IVIg. (c) 2005 Elsevier B.V. All rights reserved.
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收藏
页码：153 / 155
页数：3
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