Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms

被引：45
|
作者：
Xu, Chun [1 ,2 ]
He, Yan [1 ]
Li, Zhihao [1 ]
Nor, Yusilawati Ahmad [2 ,3 ]
Ye, Qingsong [1 ]
机构：
[1] Univ Queensland, Sch Dent, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Brisbane, Qld 4072, Australia
[3] Int Islamic Univ Malaysia, Dept Biochem Biotechnol Engn, Jalan Gombak, Kuala Lumpur 53100, Malaysia
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2018年 / 6卷 / 13期
关键词：
BACTERIAL BIOFILMS; ENZYME IMMOBILIZATION; INFECTIONS; RELEASE; RESISTANCE; PARTICLES; SPHERES; SHAPE;
D O I：
10.1039/c7tb03201c
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
The delivery of bactericidal proteins into biofilms is challenging. Hollow mesoporous silica nanoparticles with large cone-shaped pores were synthesized to deliver antimicrobial proteins into biofilms and showed enhanced antimicrobial activities.
引用
收藏
页码：1899 / 1902
页数：4
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