Parametrization histological grade white adipose tissue of the breast by the cubic spline interpolation

被引:0
|
作者
Martinez, Leslie A. [1 ,4 ]
Narea, Freddy J. [1 ]
Cedeno, Fernando [2 ]
Munoz, Aaron A. [1 ,3 ]
Reigosa, Aldo [3 ]
Bravo, Kelly [1 ]
机构
[1] Univ Carabobo, FACYT, Dept Phys, Valencia, Venezuela
[2] Univ Carabobo, FACYT, Dept Math, Valencia, Venezuela
[3] Cent Univ Venezuela, Phys Med Grad, Caracas, Venezuela
[4] Univ Carabobo, CIMBUC FCS, Ctr Med Res & Biotechnol, Valencia, Venezuela
关键词
Numerical approximation; Diffuse reflection spectroscopy; Histological grade; White adipose tissue;
D O I
10.1117/12.2026344
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
The noninvasive optical techniques have attracted considerable interest in recent years, because these techniques provide lot of information on the structure and composition of biological tissues more quickly and painlessly, in this study classifies the degrees of histological differentiation of neoplastic tissue of the breast in white adipose tissue samples through numerical pametrizacion of the diffuse reflection spectra using the Fourier series approximation. The white adipose tissue is irradiated with the spectrophotometer MiniScan XEplus and it from a mastectomy of patients with aged 38 and 50 who have a cancer lesion in the breast. The samples were provided by the pathologist with theirs medical report, it which we indicate the histological grade of tumor. We performed a parameterization algorithm where the classification criterion is the modulus of the minimum difference between the numerical approximation coefficients a(i) and average numerical approximation coefficients obtained for each histological grade (a) over bar (i). Is confirmed that the cubic spline interpolation this low-power computing lets classified into histological grades with 91% certainty the tissues under study from vertical bar a(i) - (a) over bar (i)vertical bar
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页数:7
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