Low-Temperature Synthesis and Antibacterial Activity of Hybrid Systems of Gentamicin Sulfate with Copper and Iron Nanoparticles

被引：5

作者：

Vernaya, O. I. ^{[1
]}

Shabatin, V. P. ^{[1
]}

Semenov, A. M. ^{[1
]}

Shabatina, T. I. ^{[1
]}

Melnikov, M. Ya. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119899, Russia

来源：

MOSCOW UNIVERSITY CHEMISTRY BULLETIN | 2020年 / 75卷 / 04期

基金：

俄罗斯科学基金会;

关键词：

iron nanoparticles; copper nanoparticles; gentamicin sulfate; antibacterial activity; SILVER NANOPARTICLES; ANTIBIOTICS; AG;

D O I：

10.3103/S0027131420040094

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cryochemical modification methods are used to obtain hybrid composites of the antibacterial drug gentamicin sulfate, as well as copper and iron nanoparticles, which are promising precursors of the targeted drug delivery systems. The resulting systems are antibiotic nanoparticles of 50 to 300 nm, including copper and iron nanoparticles of 1 to 20 nm (according to the results of physicochemical analysis by IR spectroscopy, X-ray diffraction analysis, dynamic light scattering, and scanning and transmission microscopy). The composites obtained showed higher antibacterial activity againstE. coli,P. aeruginosa, andB. cereuscompared to the individual components.

引用

页码：258 / 260

页数：3

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