Modeling of Neuromuscular Blockade in General Anesthesia

被引：2

作者：

Hodrea, Ramona ^{[1
]}

Morar, Radu ^{[1
]}

Nascu, Ioan ^{[1
]}

Vasian, Horatiu ^{[2
]}

机构：

[1] Tech Univ Cluj Napoca, Automat Dept, Cluj Napoca, Romania

[2] Univ Med Pharm Iuliu Hatieganu, Dept Anaesthesia & Intensive Care, Cluj Napoca, Romania

来源：

2013 8TH INTERNATIONAL SYMPOSIUM ON ADVANCED TOPICS IN ELECTRICAL ENGINEERING (ATEE) | 2013年

关键词：

Wiener model; identification; neuromuscular blockade; ROCURONIUM; ATRACURIUM; GENDER; AGE;

D O I：

10.1109/ATEE.2013.6563420

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Neuromuscular blocking agents (NMBA) play an important role in anesthesia, although they do not provide any pain relief or produce unconsciousness. A Wiener model developed for neuromuscular blockade, using input-output data recorded during surgical interventions at Regional Institute of Gastroenterology and Hepatology "Prof. Dr. Octavian Fodor" Cluj-Napoca is presented in this paper. The model consists of a 3rd order transfer function and a nonlinear static model. A nominal model was obtained and the linear part was reduced from third order to second order. The model can be used further in a model-based predictive control strategy.

引用

页数：4

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