Noggin suppression enhances in vivo bone formation

被引：0

作者：

Wan, D. C. ^{[1
]}

Pomerantz, J. H. ^{[1
]}

Brunet, L. J. ^{[1
]}

Kim, J. -B. ^{[1
]}

Chou, Y. -F. ^{[1
]}

Kwan, M. D. ^{[1
]}

Slater, B. J. ^{[1
]}

Gupta, D. M. ^{[1
]}

Wu, B. M. ^{[1
]}

Harland, R. M. ^{[1
]}

Blau, H. M. ^{[1
]}

Longaker, M. T. ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Surg, Childrens Surg Res Program, Stanford, CA 94305 USA

来源：

CRANIOFACIAL SURGERY: PROCEEDINGS OF THE TWELFTH INTERNATIONAL CONGRESS OF THE INTERNATIONAL SOCIETY OF CRANIOFACIAL SURGERY | 2007年

关键词：

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Several investigations have demonstrated a precise balance to exist between bone morphogenetic protein (BMP) agonists and antagonists, dictating BMP signaling and osteogenesis. Using RNA interference, we have previously reported that reduction of noggin enhanced BMP signaling and in vitro osteoblast bone formation. This study examined the in vivo biology of noggin-suppressed osteoblasts, in the setting of critical-sized defects in mice. Radiographic and histological analyses were employed to evaluate differences in bone regeneration across the region of injury.

引用

页码：49 / 52

页数：4

共 50 条

[1] Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation
Wan, Derrick C.
Pomerantz, Jason H.
Brunet, Lisa J.
Kim, Jae-Beom
Chou, Yu-Fen
Wu, Benjamin M.
Harland, Richard
Blau, Helen M.
Longaker, Michael T.
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (36) : 26450 - 26459
[2] Noggin suppression enhances osteogenesis of murine osteoblasts
Wan, DC
Pomerantz, J
Nacamuli, R
Siedhoff, M
Blau, H
Longaker, MT
[J]. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2005, 201 (03) : S62 - S62
[3] Noggin suppression enhances osteogenesis of murine osteoblasts
Wan, D. C.
Pomerants, J. H.
Nacamuli, R. P.
Kim, J. B.
Blau, H. M.
Longaker, M. T.
[J]. Craniofacial Surgery, 2005, : 3 - 5
[4] Noggin short interfering RNA gene transfer enhances the in vivo ectopic bone formation induced by bone morphogenetic protein-2
Takayama, K.
Suzuki, A.
Manaka, T.
Taguchi, S.
Hashimoto, Y.
Takaoka, K.
[J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2007, 22 : S392 - S392
[5] RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro
Takayama, Kazushi
Suzuki, Akinobu
Manaka, Tomoya
Taguchi, Susumu
Hashimoto, Yusuke
Imai, Yuuki
Wakitani, Shigeyuki
Takaoka, Kunio
[J]. JOURNAL OF BONE AND MINERAL METABOLISM, 2009, 27 (04) : 402 - 411
[6] RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro
Kazushi Takayama
Akinobu Suzuki
Tomoya Manaka
Susumu Taguchi
Yusuke Hashimoto
Yuuki Imai
Shigeyuki Wakitani
Kunio Takaoka
[J]. Journal of Bone and Mineral Metabolism, 2009, 27
[7] Noggin inhibits BMP-2 mediated de novo bone formation in vivo
Economides, AN
Liu, X
Gannon, FH
Shore, EM
Wang, X
Elover, G
Shiram, KB
Fytros-Sirabian, EK
Fandl, JP
Ryan, TE
Bailesy, KM
Kaplan, FS
Kimble, R
Stahl, N
[J]. BONE, 1999, 24 (04) : 429 - 429
[8] Ex Vivo Noggin Gene Therapy Inhibits Bone Formation in a Mouse Model of Postoperative Resynostosis
Cooper, Gregory M.
Usas, Arvydas
Olshanski, Anne
Mooney, Mark P.
Losee, Joseph E.
Huard, Johnny
[J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2009, 123 (02) : 94S - 103S
[9] Enhanced Osteoinductivity of Demineralized Bone Matrix with Noggin Suppression in Polymer Matrix
Chen, Chen
Rehnama, Matthew
Kim, Soyon
Lee, Chung-Sung
Zhang, Xiao
Aghaloo, Tara
Fan, Jiabing
Lee, Min
[J]. ADVANCED BIOLOGY, 2021, 5 (01):
[10] Forskolin Enhances In Vivo Bone Formation by Human Mesenchymal Stromal Cells
Doorn, Joyce
Siddappa, Ramakrishnaiah
van Blitterswijk, Clemens A.
de Boer, Jan
[J]. TISSUE ENGINEERING PART A, 2012, 18 (5-6) : 558 - 567

← 1 2 3 4 5 →