Central nervous system and head and neck imaging findings of MYC/BCL2 "double hit" B cell lymphoma

被引:3
|
作者
Khaleel, Ziyad L. [1 ]
Wright, Mathew P. [2 ]
Quigley, Edward [3 ]
Singh, T. J. [1 ]
Jones, Randall [1 ]
机构
[1] Sir Charles Gairdner Hosp, Neurol Intervent & Imaging Serv Western Australia, Nedlands, WA 6009, Australia
[2] Royal Perth Hosp, Dept Haematol, Perth, WA 6001, Australia
[3] Univ Utah, Hlth Sci Ctr, Dept Radiol, Salt Lake City, UT USA
关键词
Central nervous system; Central skull base; Head; MYC/BCL2 double hit lymphoma; Nasopharynx; Neck; Non-Hodgkin lymphoma; FEATURES; CT; MR;
D O I
10.1016/j.jocn.2013.01.029
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
MYC/BCL2 double hit lymphoma (DHL) is a rare, recently recognised and highly aggressive subtype of non-Hodgkin lymphoma, with an affinity to involve the central nervous system and the head and neck either at initial presentation or during relapse. We present a case of 43-year-old woman with MYC/BCL2 DHL relapse in the nasopharynx with extensive spread to the neck, skull base, and the central nervous system. To our knowledge, this is the first reported case in the literature describing the MRI and CT scan findings and the profound pattern of disease involvement of this rare neoplasm. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:326 / 327
页数:2
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