Synthesis of 3-aryl and 3-heterocyclic quinoxalin-2-ylamines via Pd-catalyzed cross-coupling reactions

被引：1

作者：

Li, JJ ^{[1
]}

Yue, WS ^{[1
]}

机构：

[1] Warner Lambert Co, Parke Davis Pharmaceut Res Div, Dept Med Chem, Ann Arbor, MI 48105 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 24期

关键词：

quinoxalines; the Stille reaction; the Suzuki reaction; regiochemistry;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Facile and high yielding Suzuki and Stille cross-coupling reactions of 3-bromo-quinoxalin-2-ylamines were developed to synthesize a variety of novel and diversely functinalized 3-aryl and 3-heterocyclic quinoxalin-2-ylamines. The preparation of the substrates and the remarkable impact that substituents have on the regiochemical outcome are discussed. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4507 / 4510

页数：4

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