Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode

被引：0
|
作者：
Hejdukova, Martina [1 ,2 ,3 ]
Spacek, Jan [1 ,2 ,3 ]
Fojta, Mirostav [1 ,2 ,3 ]
Havran, Ludek [1 ]
Renciuk, Daniel [1 ]
机构：
[1] Masaryk Univ, Fac Sci, Kamenice 753-5, Brno 62500, Czech Republic
[2] Czech Acad Sci, Inst Biophys, Kralovopolska 135, Brno 61265, Czech Republic
[3] Masaryk Univ, CEITEC Cent European Inst Technol, Kamenice 5, Brno 62500, Czech Republic
来源：
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE MODERN ELECTROCHEMICAL METHODS XXXVIII | 2018年
关键词：
Oligonucleotides; Pyrolytic graphite electrode; Linear sweep voltammetry;
D O I：
暂无
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA.
引用
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页码：74 / 76
页数：3
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