Increasing HPV Vaccination Coverage Through Provider-Based Interventions

With discouragingly low vaccination rates for human papillomavirus (HPV), we sought to improve the HPV vaccine completion rate for adolescents by increasing the consistency and quality of provider recommendations. Baseline data was extracted for vaccine completion rates among patients aged 13 to 17 years. Quality improvement measures led to interventions targeting factors associated with vaccine noncompletion, in particular, weaknesses in provider recommendations and patient characteristics most strongly correlated with missed vaccination opportunities. Vaccine completion rates increased overall from 50.9% to 61.7% (P < .05), an increase seen in both males (42.6% to 57.3%, P < .001) and females (60.0% to 66.5%, P = .04). One-dose rates improved to 88.4% for males (P = .02) and 91.5% for females (P = .43). Vaccination also occurred more consistently, increasing from 77.5% of visits (95% CI 71.2-83.0) before study onset to 90.9% of visits (95% CI 85.4%-94.8%) afterward (P < .01). HPV vaccination rates can increase through focused provider-level prompts and by offering the vaccine consistently.