Neuropathic Pain: Some Clues for Future Drug Treatments

被引：6

作者：

Banos, J. E. ^{[1
]}

Sanchez, G. ^{[1
]}

Berrendero, F. ^{[1
]}

Maldonado, R. ^{[1
]}

机构：

[1] Univ Pompeu Fabra, Fac Hlth & Life Sci, Dept Expt & Hlth Sci, Dr Aiguader 80, Barcelona 08003, Spain

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2003年 / 3卷 / 07期

关键词：

Pain; neuropathic pain; analgesics; pathophysiology; allodynia; hyperalgesia; experimental models; new drugs;

D O I：

10.2174/1389557033487773

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Neuropathic pain is still far from being adequately dealt with. Under this name, several clinical entities have been considered and most of them only share several painful ailments. At present, the available treatments can only alleviate the pain of roughly half of the patients, and their effectiveness is often limited by the appearance of the intolerable side effects. In this review, we will consider the pathophysiology of neuropathic pain to understand the basis of pharmacological treatments that are currently being investigated. Some examples of these drugs will also be considered.

引用

页码：719 / 727

页数：9

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