Potential strategies for combating COVID-19

被引:8
|
作者
Shamim, Saba [1 ]
Khan, Maryam [1 ]
Kharaba, Zelal Jaber [2 ]
Ijaz, Munazza [1 ]
Murtaza, Ghulam [3 ]
机构
[1] Univ Lahore, Inst Mol Biol & Biotechnol, Lahore, Pakistan
[2] Al Ain Univ Sci & Technol, Coll Pharm, Dept Clin Sci, Abu Dhabi, U Arab Emirates
[3] COMSATS Univ Islamabad, Dept Pharm, Lahore Campus, Islamabad 54000, Pakistan
关键词
ACUTE RESPIRATORY SYNDROME; EBOLA-VIRUS DISEASE; MERS-COV INFECTION; CONVALESCENT PLASMA; CORONAVIRUS OUTBREAK; INFLUENZA PNEUMONIA; GLOBAL HEALTH; DOUBLE-BLIND; SARS; ANTIBODY;
D O I
10.1007/s00705-020-04768-3
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatalities all over the world (WHO). In this review, we elaborate all currently available data that shed light on possible methods for treatment of COVID-19, such as antiviral drugs, corticosteroids, convalescent plasma, and potentially effective vaccines. Additionally, ongoing and discontinued clinical trials that have been carried out for validating probable treatments for COVID-19 are discussed. The review also elaborates the prospective approach and the possible advantages of using convalescent plasma and stem cells for the improvement of clinical symptoms and meeting the demand for an instantaneous cure.
引用
收藏
页码:2419 / 2438
页数:20
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