PRIMARY RESULT OF THE 1ST THERAPEUTIC INTERVENTIONS IN MALIGNANT EFFUSION (TIME1) TRIAL: A 2 x 2 FACTORIAL, RANDOMISED TRIAL OF CHEST TUBE SIZE AND ANALGESIC STRATEGY FOR PLEURODESIS IN MALIGNANT PLEURAL EFFUSION

被引：2

作者：

Rahman, N. M. ^{[1
]}

Pepperell, J. ^{[2
]}

Rehal, S. ^{[3
]}

Saba, T. ^{[4
]}

Tang, A. ^{[4
]}

Ali, N. ^{[5
]}

West, A. ^{[6
]}

Hettiarachchi, G. ^{[6
]}

Mukherjee, D. ^{[7
]}

Samuel, J. ^{[7
]}

Bentley, A. ^{[8
]}

Dowson, L. ^{[9
]}

Miles, J. ^{[10
]}

Ryan, F. ^{[11
]}

Yoneda, K. ^{[12
]}

Chauhan, A. ^{[13
]}

Corcoran, J. ^{[1
]}

Psallidas, I. ^{[1
]}

Wrightson, J. M. ^{[1
]}

Hallifax, R. ^{[1
]}

Davies, H. E. ^{[14
]}

Lee, Y. C. G. ^{[15
,16
]}

Hedley, E. L. ^{[1
]}

Seaton, D. ^{[17
]}

Russell, N. ^{[1
]}

Chapman, M. ^{[1
]}

McFadyen, B. M. ^{[1
]}

Shaw, R. A. ^{[1
]}

Davies, R. J. O. ^{[1
]}

Maskell, N. A. ^{[18
]}

Nunn, A. J. ^{[3
]}

Miller, R. F. ^{[19
]}

机构：

[1] Oxford Resp Trials Unit, Oxford, England

[2] Musgrove Pk Hosp, Somerset Lung Ctr, Taunton, Somerset, England

[3] UCL, Clin Trials Unit, MRC, London, England

[4] Blackpool Fylde & Wyre Hosp NHS Trust, Blackpool, England

[5] Kings Mill Hosp, Mansfield, England

[6] Medway Maritime Hosp, Gillingham, England

[7] Basildon Univ Hosp, Basildon, England

[8] Univ Hosp South Manchester NHS Trust, Manchester, Lancs, England

[9] Royal Wolverhampton Hosp NHS Trust, Wolverhampton, England

[10] Rotherham Gen Hosp, Rotherham, S Yorkshire, England

[11] Vancouver Coastal Hlth, Vancouver, BC, Canada

[12] UC Davis Med Ctr, Sacramento, CA USA

[13] Queen Alexandra Hosp, Portsmouth, Hants, England

[14] Cardiff & Vale Univ Hlth Board, Cardiff, S Glam, Wales

[15] Univ Western Australia, Sch Med, Perth, WA 6009, Australia

[16] Univ Western Australia, CAARR, Perth, WA 6009, Australia

[17] Ipswich Hosp, Dept Resp Med, Ipswich, Suffolk, England

[18] Univ Bristol, Southmead Hosp, Dept Clin Sci, Acad Resp Unit, Bristol, Avon, England

[19] UCL, Res Dept Infect & Populat Hlth, Inst Epidemiol & Healthcare, London, England

来源：

THORAX | 2015年 / 70卷

关键词：

D O I：

10.1136/thoraxjnl-2015-207770.26

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

S20

引用

页码：A15 / A16

页数：2

共 9 条

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Bentley, A.
Dowson, L.
Miles, J.
Ryan, F.
Yoneda, K. Y.
Chauhan, A.
Corcoran, J.
Davies, H. E.
Hallifax, R.
Psallidas, I.
Wrightson, J. M.
Maskell, N. A.
Kahan, B. C.
Rehal, S.
Lee, G. Y. C.
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[2] The second therapeutic intervention in malignant effusion trial (TIME2): A randomised controlled trial to assess the efficacy and safety of patient controlled malignant pleural effusion drainage by indwelling pleural catheter compared to chest drain and talc slurry pleurodesis
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[3] Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion The TIME1 Randomized Clinical Trial
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[6] SURVIVAL AND PLEURODESIS OUTCOME IN PATIENTS WITH MALIGNANT PLEURAL EFFUSION - POST-HOC ANALYSIS FROM THE TIME-1 TRIAL
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[J]. THORAX, 2018, 73 : A82 - A83
[7] Phase II study of efficacy of bevacizumab plus chemotherapy in management of malignant pleural effusion in non-squamous non-small cell lung cancer patients with malignant pleural effusion (MPE) unsuccessfully controlled by tube drainage or pleurodesis (NEJ-13-2 trial)
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