Bone Morphogenetic Protein-2 and Vascular Endothelial Growth Factor in Bone Tissue Regeneration: New Insight and Perspectives

被引：33
|
作者：
Aryal, Rajendra [1 ]
Chen, Xiao-peng [1 ]
Fang, Cheng [1 ]
Hu, Yong-cheng [2 ]
机构：
[1] Tianjin Med Univ, Tianjin, Peoples R China
[2] Tianjin Hosp, Dept Bone Oncol, Tianjin 300211, Peoples R China
来源：
ORTHOPAEDIC SURGERY | 2014年 / 6卷 / 03期
关键词：
Bone morphogenetic protein-2; Bone tissue regeneration; Vascular endothelial growth factor; MESENCHYMAL STEM-CELLS; SIZE DEFECT MODEL; FORMATION IN-VIVO; FACTOR DELIVERY; OSTEOGENIC DIFFERENTIATION; GENE-EXPRESSION; STROMAL CELLS; OSTEOBLAST DIFFERENTIATION; PROGENITOR CELLS; FACTOR RELEASE;
D O I：
10.1111/os.12112
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
The study of bone tissue regeneration in orthopaedic diseases has stimulated great interest among bone tissue engineering specialists and orthopaedic surgeons. Combinations of biomaterials, growth factors and stem cells for repairing bone have been much studied and researched, yet remain a challenge for both scientists and clinicians pursuing regenerative medicine. The purpose of this review was to elucidate the role of sequential release of bone morphogenetic protein-2 and vascular endothelial growth factor in producing better outcomes in the field of bone tissue regeneration.
引用
收藏
页码：171 / 178
页数：8
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