Multi-peak phenomenon of insect cell infection with baculovirus at low multiplicity of infection

被引：1
|
作者：
Zhang, YH [1 ]
机构：
[1] Wuhan Inst Technol, Hubei Key Lab Novel Chem Reactor & Green Chem Tec, Wuhan 430073, Peoples R China
[2] Ben Gurion Univ Negev, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel
来源：
ACTA BIOCHIMICA ET BIOPHYSICA SINICA | 2005年 / 37卷 / 12期
关键词：
insect cell; Anticarsia gemmatalis multicapsid nucleopolyhedrovirus (AgMNPV); infection; multiplicity of infection (MOI); dynamics;
D O I：
10.1111/j.1745-7270.2005.00115.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this communication we report the infection of armyworm Spodopterafrugiperda IPLB-Sf-21 cells with Anticarsia gemmatalis multicapsid nucleopolyhedrovirus at low multiplicity of infection (MOI). The temporal variation of the extra-cellular virus and of the unstained cell was followed. The series of peaks in the virus concentration and the unstained cells count were used in order to infer the dynamic mechanism of the infection at low MOI. This mechanism can be used as the basis for the future formulation of a mathematical model of the process.
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页码：857 / 861
页数：5
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