C-glycosylated biphenyls:: The Stille coupling reaction of C-glycosylated aryl tins with aryl bromides

被引:11
|
作者
Kuribayashi, T [1 ]
Gohya, S [1 ]
Mizuno, Y [1 ]
Satoh, S [1 ]
机构
[1] Sankyo Co Ltd, Exploratory Chem Res Labs, Shinagawa Ku, Tokyo 1408710, Japan
关键词
D O I
10.1080/07328309908544003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
C-glycosylated biphenyls were prepared by the palladium-mediated cross-coupling reaction of C-glycosylated aryl tins with variously substituted aryl bromides, which will provide physiologically stable glycomimetics of various glycoepitopes. A C-sialylated biphenyl, a glycomimetic of biologically significant sialosides, is also available by this method.
引用
收藏
页码:383 / 392
页数:10
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