Coronary Computed Tomography Angiography

In this issue of the Journal, Budoff et al. (1) publish results from the ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial comparing non-invasive coronary computed tomography angiography (CCTA) with invasive quantitative coronary angiography (QCA) for definition of atherosclerotic luminal narrowing at the 50% and/or 70% stenosis levels. At first glance my reaction was, "Oh, no, not another 64-slice CT scan 'validation' report looking at sensitivity (Se)/specificity (Sp) for finding obstructive coronary disease! Didn't I just read a similar report in JACC, JAMA, Circulation, etc.!" However, this was and is not the case.