Synthesis and characterization of random and regular L-lysine-based polyamides

This paper deals with the synthesis of polyamides based on the natural diamine, L-lysine, on the one hand, and diacids, adipic or glutaric, on the other hand. They were obtained by polycondensation of active diesters, pentachlorophenyl and pentafluorophenyl esters. L-Lysine being non-symmetrical, aregic (random) and syndioregic (''head-to-head, tail-to-tail'') poly(adipoyl-L-lysine)s and poly(glutaroyl-L-lysine)s were obtained with molecular weights higher than 15000; isoregic (''head-to-tail'') poly(adipoyl-L-lysine)s and poly(glutaroyl-L-lysine)s were prepared with lower molecular weights.