Acute interstitial nephritis of fluindione: About three cases

被引:4
|
作者
Beauchamp, Christine [1 ]
Enache, Ioana [1 ]
Haskour, Abraham [1 ]
Martin, Laurent [2 ]
机构
[1] Ctr Hosp Pierre Beregovoy, Dept Nephrol Dialyse, F-58033 Nevers, France
[2] Fac Med, Lab Anatomopathol, F-21000 Dijon, France
来源
NEPHROLOGIE & THERAPEUTIQUE | 2008年 / 4卷 / 05期
关键词
Fluindione; Immunoallergic; Acute renal failure; Interstitial nephropathy;
D O I
10.1016/j.nephro.2008.02.003
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Acute interstitial nephritis is a frequent cause of acute renal failure, representing about 10% of all biopsied cases. Early recognition of drug-induced acute immunoallergic interstitial nephritis prevents the development of severe chronic renal injury. The list of imputable drugs includes phenindione, a vitamin K antagonist. Fluindione which is also an indanedione derivative is another vitamin K antagonist. We report three biopsy-proved cases of fluindione related acute interstitial nephritis with recovery of renal function after drug withdrawal and prednisone therapy. (C) 2008 Elsevier Masson SAS et Association Societe de Nephrologie. Tous droits reserves.
引用
收藏
页码:339 / 346
页数:8
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