An efficient synthesis of unsymmetrical 1,1-bis(silyl)ethenes

被引：12
|
作者：
Hreczycho, G [1 ]
Pawluc, P [1 ]
Marciniec, B [1 ]
机构：
[1] Adam Mickiewicz Univ, Fac Chem, Dept ORganomet Chem, PL-60780 Poznan, Poland
来源：
SYNTHESIS-STUTTGART | 2006年 / 8卷 / 08期
关键词：
vinylsilanes; silylative coupling; amino alcohol; Grignard reactions; organometallic reagents;
D O I：
10.1055/s-2006-926406
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new convenient and effective method for the synthesis of unsymmetrical 1,1-bis(silyl)ethenes is described. The synthetic methodology involves selective silylative coupling cyclization of N-methyl-N-(dimethylvinylsilyi)-2-(dimethylvinylsilyloxy)ethanamine catalyzed by a ruthenium hydride complex and subsequent one-pot reaction of the cyclic bis(silyl)derivative with Grignard reagents followed by alcoholysis. As a result, a variety of 1,1-bis(silyl)ethenes containing different substituents at the silicon atoms were produced in regiocontrolled manner with considerably high efficiency.
引用
收藏
页码：1370 / 1374
页数：5
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