Effects of pulsed magnetic field chronic exposure on some hematological parameters in mice

In this experimental study, the hematological effects Of Pulsed electromagnetic fields (EMF) chronic exposure were investigated oil mice. Sixty, 6 week old male Swiss mice, weighing 40-45, were used. and were divided into two groups: in one group, animals (n=30) were exposed to pulsed EMF (60 Hz, intensity 3 mu T, twelve hours by day) for a 120 day-period, whereas the second group (n=30) Was used as control. On days 15, 30, 90 and 120. samples were taken by cardiac puncture for the hematological analysis (Red blood cell and white blood cell Counts, leukocyte distribution). Whereas no significant difference was noted between control and exposed animals at the 15th and the 30th days, a macrocytic anemia characterized by decreases of hemoglobin concentration, hematocrit Values and erythrocyte counts and by the increase of mean corpuscular volume, occurred in the exposed animals oil day 90. Furthermore. they have shown significant reductions of leukocyte. lymphocyte and neutrophil Counts. while monocyte counts were increased. On day 120, these leukocyte alterations were still observed. whereas erythrocyte parameters became close to control Values. These results suggest that pulsed electromagnetic fields (60 Hz and 3 mu T) affect the hematological parameters of mice. probably by reducing proliferation and differentiation of marrow stem cells.