Virulence factors of Toxoplasma gondii

被引：49
|
作者：
Dubremetz, Jean Francois [1 ]
Lebrun, Maryse [1 ]
机构：
[1] Univ Montpellier 2, CNRS, UMR 5235, F-34095 Montpellier 5, France
来源：
MICROBES AND INFECTION | 2012年 / 14卷 / 15期
关键词：
Toxoplasma gondii; Virulence; Genetics; Infection; HOST-CELL INVASION; DENSE GRANULE PROTEIN; PARASITOPHOROUS VACUOLE; TARGETED DISRUPTION; RHOPTRY PROTEINS; MOVING JUNCTION; ANTIGEN; SURFACE; FAMILY; INDUCTION;
D O I：
10.1016/j.micinf.2012.09.005
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Toxoplasma gondii virulence is dependent on factors involved in either parasite-host cell interaction, or in host immune response. It is essentially defined in the mouse and little is known concerning human infection. The genetic dependence of virulence is a growing field, benefiting from the recent development of research of the population structure of T gondii. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：1403 / 1410
页数：8
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