Inner Secrets of the Respirasome

被引:9
|
作者
Melber, Andrew [1 ]
Winge, Dennis R. [1 ]
机构
[1] Univ Utah, Hlth Sci Ctr, Salt Lake City, UT 84132 USA
关键词
MITOCHONDRIAL COMPLEX I; PROTEIN; SUPERCOMPLEX; ARCHITECTURE;
D O I
10.1016/j.cell.2016.11.025
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Structure determination by cryo-electron microscopy has approached atomic resolution and helped solve structures of large membrane-protein complexes that resisted crystallography. The 4.0 angstrom cryo-EM structure of one of the most intricate enzyme systems, the respirasome, in the mitochondrial inner membrane is reported in this issue of Cell.
引用
收藏
页码:1450 / 1452
页数:3
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