Electrophilic fluorination using a hypervalent iodine reagent derived from fluoride

被引：83
|
作者：
Geary, Gemma C. [1 ]
Hope, Eric G. [1 ]
Singh, Kuldip [1 ]
Stuart, Alison M. [1 ]
机构：
[1] Univ Leicester, Dept Chem, Leicester LE1 7RH, Leics, England
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 81期
关键词：
SELECTIVE FLUORINATION; BETA-KETOESTERS; TRIFLUOROMETHYLATION; SELECTFLUOR; AGENTS; SALTS; BIS(TETRAFLUOROBORATE); FAMILY; HF;
D O I：
10.1039/c3cc44792h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The air and moisture stable fluoroiodane 8, readily prepared on a 6 g scale by nucleophilic fluorination of the hydroxyiodane 7 with TREAT-HF, has been used as an electrophilic fluorinating reagent for the first time to monofluorinate 1,3-ketoesters and difluorinate 1,3-diketones in good isolated yields.
引用
收藏
页码：9263 / 9265
页数：3
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