Nucleophilic fluoroalkylation of terminal vinyl triflones with SO2CF3 as a removable activating group

被引：13
|
作者：
Tian, Ping-ping [1 ]
Xiao, Hong-qing [1 ]
Wang, Lu [1 ]
Yu, Yingxin [2 ]
Huang, Yangen [1 ]
机构：
[1] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Key Lab Sci & Technol Ecotext, Minist Educ, 2999 North Renmin Lu, Shanghai 201620, Peoples R China
[2] Guangdong Univ Technol, Guangdong Key Lab Environm Catalysis & Hlth Risk, Guangzhou Key Lab Environm Catalysis & Pollut Con, Sch Environm Sci & Engn,Inst Environm Hlth & Poll, Guangzhou 510006, Guangdong, Peoples R China
来源：
TETRAHEDRON LETTERS | 2019年 / 60卷 / 15期
基金：
中国国家自然科学基金;
关键词：
Difluoromethylation; Michael addition; Difluoromethylene phosphabetaine; Vinyl triflones; ALDEHYDE-DERIVED HYDRAZONES; C-H DIFLUOROALKYLATION; TRIFLUOROMETHYLATION; FLUORINE; ALKENES; PERFLUOROALKYLATION; DIFLUOROCARBENE; TRANSMISSION; CONVERSION; CHEMISTRY;
D O I：
10.1016/j.tetlet.2019.03.015
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Terminal vinyl triflones served as excellent Michael addition acceptors which readily reacted with difluoromethylene phosphabetaine and di- or mono-fluoroalkyl bromides to afford compounds containing CF2 or CF groups. This fluoroalkylation is characterized by mild reaction conditions, ready availability of reagents and excellent functional-group tolerance. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1015 / 1018
页数：4
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