Learning Objectives: After reading this article, the participant should be able to: 1. Discuss the options for reconstruction of scalp, skull, orbit, and maxilla defects. 2. Describe the core principles to obtaining a sound result. Summary: Orbitomaxillary, skull, scalp, and hair restoration covers a broad segment of reconstructive surgery. The purpose of this article is to review considerations in available options for reconstruction, flap selection, relevant anatomy, and potential hazards. Although there are a variety of methods available to treat these complex defects, core principles are presented as a guide to obtaining a sound result specific to the priorities appropriate to an individual patient. (Plast. Reconstr. Surg. 131: 411e, 2013.)