Separation of mAb Isoforms Using Controlled pH Gradients and Ion Exchange Chromatography Columns

被引：0
|
作者：
Chakrabarti, Atis [1 ]
机构：
[1] Tosoh Bioscience LLC, King Of Prussia, PA 19406 USA
来源：
LC GC NORTH AMERICA | 2012年
关键词：
D O I：
暂无
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
引用
收藏
页码：16 / 17
页数：2
相关论文
共 50 条
  • [1] Separation of Protein Charge Variants with Induced pH Gradients Using Anion Exchange Chromatographic Columns
    Pabst, Timothy M.
    Carta, Giorgio
    Ramasubramanyan, Natrajan
    Hunter, Alan K.
    Mensah, Paul
    Gustafson, Mark E.
    BIOTECHNOLOGY PROGRESS, 2008, 24 (05) : 1096 - 1106
  • [2] Charge heterogeneity profiling of monoclonal antibodies using low ionic strength ion-exchange chromatography and well-controlled pH gradients on monolithic columns
    Talebi, Mohammad
    Nordborg, Anna
    Gaspar, Andras
    Lacher, Nathan A.
    Wang, Qian
    He, Xiaoping Z.
    Haddad, Paul R.
    Hilder, Emily F.
    JOURNAL OF CHROMATOGRAPHY A, 2013, 1317 : 148 - 154
  • [3] Pisep, A Powerful New Ion Exchange Chromatography Using Controlled Ph Gradients For Separating Proteins On Anionic And Cationic Stationary Phases
    Hirsh, Allen
    Tsonev, Latchezar I.
    BIOPHYSICAL JOURNAL, 2009, 96 (03) : 635A - 635A
  • [4] Application of linear pH gradients for the modeling of ion exchange chromatography: Separation of monoclonal antibody monomer from aggregates
    Kluters, Simon
    Wittkopp, Felix
    Joehnck, Matthias
    Frech, Christian
    JOURNAL OF SEPARATION SCIENCE, 2016, 39 (04) : 663 - 675
  • [5] Displacement effect in ion exchange chromatography systems using retained stepwise pH gradients.
    Narahari, CR
    Frey, DD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 216 : U297 - U297
  • [6] SEPARATION OF BASES AND AMINO ACIDS BY DISPLACEMENT CHROMATOGRAPHY ON ION-EXCHANGE COLUMNS
    PARTRIDGE, SM
    DISCUSSIONS OF THE FARADAY SOCIETY, 1949, (07): : 296 - 305
  • [7] Determination of amines by ion chromatography using cation exchange columns
    Gandhi, JC
    LC GC NORTH AMERICA, 2003, : 57 - 57
  • [8] Fast ion chromatography using short anion exchange columns
    Tyrrell, Eadaoin
    Shellie, Robert A.
    Hilder, Emily F.
    Pohl, Christopher A.
    Haddad, Paul R.
    JOURNAL OF CHROMATOGRAPHY A, 2009, 1216 (48) : 8512 - 8517
  • [9] The Effect of pH and Temperature on Lysozyme Separation in Ion-exchange Chromatography
    Ko, Kwan-Young
    Kim, In-Ho
    KOREAN CHEMICAL ENGINEERING RESEARCH, 2014, 52 (01): : 98 - 105
  • [10] Evaluation of preparative ion exchange and multimodal chromatography for separation of charge variants in the mAb purification process
    Gronberg, Anna
    Bjorkman, Tomas
    Karf, Lena
    Ljunglof, Anders
    Heldin, Eva
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
12345