Metformin, Microbes, and Aging

被引：9
|
作者：
Storelli, Gilles [1 ]
Tefit, Melisandre [1 ]
Leulier, Francois [1 ]
机构：
[1] Univ Lyon 1, IGFL, Ecole Normale Super Lyon, CNRS UMR 5242, F-69364 Lyon 07, France
来源：
CELL METABOLISM | 2013年 / 17卷 / 06期
关键词：
C; ELEGANS; LIFE-SPAN;
D O I：
10.1016/j.cmet.2013.05.014
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The mechanisms underlying the biological activity of metformin, a widely prescribed drug to treat type 2 diabetes, remain elusive. In a recent issue of Cell, Cabreiro et al. report that in C. elegans, metformin indirectly impacts lifespan by altering the methionine metabolism of its microbial partner E. coli (Cabreiro et al., 2013).
引用
收藏
页码：809 / 811
页数：4
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