Medication Detection by a Combinatorial Fluorescent Molecular Sensor

被引：71
|
作者：
Rout, Bhimsen [1 ]
Unger, Linor [1 ]
Armony, Gad [1 ]
Iron, Mark A. [2 ]
Margulies, David [1 ]
机构：
[1] Weizmann Inst Sci, Dept Organ Chem, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Dept Chem Res Support, IL-76100 Rehovot, Israel
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 50期
关键词：
analytical methods; combinatorial sensors; fluorescent probes; molecular devices; photophysics; RECEPTORS CREATE PATTERNS; ON-A-MOLECULE; BORONIC ACID; DIFFERENTIAL RECEPTORS; HALF-SUBTRACTOR; LOGIC; ARRAY; IDENTIFICATION; RECOGNITION; PROTEINS;
D O I：
10.1002/anie.201206374
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Working together to uncover the truth: A molecule-sized diagnostic system combining several recognition elements and four fluorescence-emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high-throughput manner. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：12477 / 12481
页数：5
相关论文
共 50 条
  • [1] Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor
    Hatai, Joydev
    Motiei, Leila
    Margulies, David
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (06) : 2136 - 2139
  • [2] Analyzing Amyloid Beta Aggregates with a Combinatorial Fluorescent Molecular Sensor
    Margulies, D. (david.margulies@weizmann.ac.il), 1600, American Chemical Society (139):
  • [3] Fluorescent Molecular Sensor for the Detection of Cadmium in Basil Roots
    Reyes, Yulieth C. R.
    Rouf, Tahrima B.
    Torres, Omar E.
    Gonzalez, Edgar E.
    ACS AGRICULTURAL SCIENCE & TECHNOLOGY, 2022, 2 (01): : 144 - 152
  • [4] Dipodal Molecular Device as Fluorescent Sensor for Na(I) Detection
    Dangi, V.
    Baral, M.
    Kanungo, B. K.
    JOURNAL OF APPLIED SPECTROSCOPY, 2020, 87 (05) : 893 - 903
  • [5] Dipodal Molecular Device as Fluorescent Sensor for Na(I) Detection
    V. Dangi
    M. Baral
    B. K. Kanungo
    Journal of Applied Spectroscopy, 2020, 87 : 893 - 903
  • [6] Use a Fluorescent Molecular Sensor for the Detection of Pesticides and Herbicides in Water
    Delattre, Francois
    Cazier, Francine
    Cazier, Fabrice
    Tine, Alphonse
    CURRENT ANALYTICAL CHEMISTRY, 2009, 5 (01) : 48 - 52
  • [7] Combinatorial Fluorescent Molecular Sensors: The Road to Differential Sensing at the Molecular Level
    Rout, Bhimsen
    Motiei, Leila
    Margulies, David
    SYNLETT, 2014, 25 (08) : 1050 - 1054
  • [8] Fluorescent molecular sensor for drug discovery
    Zlokarnik, G
    ANALYTICAL CHEMISTRY, 1999, 71 (09) : 322A - 328A
  • [9] A ratiometric fluorescent sensor for the detection of phosphate
    Liu, Jiayi
    Liu, Yibing
    Wang, Wei
    Zhang, Siqi
    Tang, Li
    Ma, Pinyi
    Song, Daqian
    Fei, Qiang
    LUMINESCENCE, 2023, 38 (02) : 152 - 158
  • [10] Multi-ion detection and molecular switching behaviour of reversible dual fluorescent sensor
    Basheer, Sabeel M.
    Muralisankar, M.
    Anjana, T. V.
    Aneesrahman, K. N.
    Sreekanth, Anandaram
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 182 : 95 - 104
12345