EFFECTS OF TOFACITINIB ON MRI ENDPOINTS IN METHOTREXATE-NAIVE EARLY RHEUMATOID ARTHRITIS: A PHASE 2 MRI STUDY WITH SEMI-QUANTITATIVE AND QUANTITATIVE ENDPOINTS

被引：0
|
作者：
Conaghan, P. G. [1 ]
Ostergaard, M. [2 ]
Bowes, M. A. [3 ]
Wu, C. [4 ]
Fuerst, T. [4 ]
van der Heijde, D. [5 ]
Hrycaj, P. [6 ]
Xie, Z. [7 ]
Zhang, R. [7 ]
Wyman, B. T. [7 ]
Bradley, J. [7 ]
Soma, K. [7 ]
Wilkinson, B. [7 ]
机构：
[1] Univ Leeds UK, Leeds, W Yorkshire, England
[2] Copenhagen Univ Hosp, Copenhagen Ctr Arthrit Res, Glostrup, Denmark
[3] Imorphics Ltd, Manchester, Lancs, England
[4] BioClinica Inc, Newark, CA USA
[5] Leiden Univ, Med Ctr, Leiden, Netherlands
[6] Poznan Univ Med Sci, Poznan, Poland
[7] Pfizer Inc, Groton, CT 06340 USA
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2015年 / 74卷
关键词：
D O I：
10.1136/annrheumdis-2015-eular.3505
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
SAT0222
引用
收藏
页码：738 / 738
页数：1
相关论文
共 50 条
  • [1] Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques
    Conaghan, Philip G.
    Ostergaard, Mikkel
    Bowes, Michael A.
    Wu, Chunying
    Fuerst, Thomas
    van der Heijde, Desiree
    Irazoque-Palazuelos, Fedra
    Soto-Raices, Oscar
    Hrycaj, Pawel
    Xie, Zhiyong
    Zhang, Richard
    Wyman, Bradley T.
    Bradley, John D.
    Soma, Koshika
    Wilkinson, Bethanie
    ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 (06) : 1024 - 1033
  • [2] Efficacy of tofacitinib monotherapy in methotrexate-naive patients with early or established rheumatoid arthritis
    Fleischmann, Roy M.
    Huizinga, Tom W. J.
    Kavanaugh, Arthur F.
    Wilkinson, Bethanie
    Kwok, Kenneth
    DeMasi, Ryan
    van Vollenhoven, Ronald F.
    RMD OPEN, 2016, 2 (02):
  • [3] Effects of Tofacitinib on Bone Marrow Edema, Synovitis, and Erosive Damage in Methotrexate-Naive Patients with Early Active Rheumatoid Arthritis (Duration ≤2 Years): Results of an Exploratory Phase 2 MRI Study.
    Conaghan, Philip G.
    Ostergaard, M.
    Wu, C.
    van der Heijde, D.
    Irazoque-Palazuelos, F.
    Hrycaj, P.
    Xie, Z.
    Zhang, R.
    Wyman, B. T.
    Bradley, J. D.
    Soma, K.
    Wilkinson, B.
    ARTHRITIS & RHEUMATOLOGY, 2014, 66 : S519 - S520
  • [4] Evaluation of a semi-quantitative MRI scoring method in psoriatic arthritis
    Anandarajah, AP
    Seo, GS
    Monu, JU
    Ritchlin, CT
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 122 (03) : A46 - A46
  • [5] Magnetic Resonance Imaging (MRI)-Based Semi-Quantitative Methods for Rheumatoid Arthritis: From Scoring to Measurement
    Salaffi, Fausto
    Carotti, Marina
    Di Carlo, Marco
    Ceccarelli, Luca
    Farah, Sonia
    Poliseno, Anna Claudia
    Di Matteo, Andrea
    Bandinelli, Francesca
    Giovagnoni, Andrea
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (14)
  • [6] EFFECTS OF TOFACITINIB MONOTHERAPY VERSUS METHOTREXATE ON PATIENT-REPORTED OUTCOMES IN THE 2-YEAR PHASE 3 ORAL START TRIAL IN METHOTREXATE-NAIVE PATIENTS WITH RHEUMATOID ARTHRITIS
    Alten, R.
    Strand, V.
    Fleischmann, R.
    Koncz, T.
    Zwillich, S.
    Bradley, J.
    Gruben, D.
    Wilkinson, B.
    Krishnaswami, S.
    Wallenstein, G.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 118 - 119
  • [7] Hepatic fibrosis in rheumatoid arthritis treated with methotrexate: Application of a semi-quantitative scoring system.
    Richard, S
    Guerret, S
    Gerard, F
    Tebib, JG
    Vignon, E
    ARTHRITIS AND RHEUMATISM, 1998, 41 (09): : S157 - S157
  • [8] RELATIONSHIP BETWEEN DIFFERENT CLINICAL MEASUREMENTS AND PATIENT-REPORTED OUTCOMES: RESULTS FROM A PHASE 3 STUDY OF TOFACITINIB OR METHOTREXATE IN METHOTREXATE-NAIVE PATIENTS WITH RHEUMATOID ARTHRITIS
    Fleischmann, R.
    Strand, V.
    Wilkinson, B.
    Kwok, K.
    Bananis, E.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : 259 - 260
  • [9] Hepatic fibrosis in rheumatoid arthritis patients treated with methotrexate: application of a new semi-quantitative scoring system
    Richard, S
    Guerret, S
    Gerard, F
    Tebib, JG
    Vignon, E
    RHEUMATOLOGY, 2000, 39 (01) : 50 - 54
  • [10] Evaluating potential for AI automation of quantitative and semi-quantitative MRI scoring in arthritis, especially at the knee: a systematic literature review
    Mcdonald, Steel M.
    Felfeliyan, Banafshe
    Hassan, Ali
    Kuepper, Jessica C.
    El-Hajj, Rehab
    Wichuk, Stephanie
    Aneja, Ashmeen
    Kwok, Cherise
    Zhang, Cindy X. Y.
    Jans, Lennart
    Herregods, Nele
    Hareendranathan, Abhilash R.
    Jaremko, Jacob L.
    SKELETAL RADIOLOGY, 2025,
12345