Drug mediated S-glutathionylation of PDI leads to alterations in secondary structure, inhibition of isomerase activity, and triggers ER-stress induced apoptosis

被引:0
|
作者
Townsend, Danyelle M. [1 ]
Manevich, Yefim [2 ]
Hutchens, Steven
Tew, Kenneth D. [2 ]
机构
[1] Med Univ S Carolina, Dept Pharmaceut & Biomed Sci, Charleston, SC 29425 USA
[2] Med Univ S Carolina, Dept Cell & Mol Pharmacol & Expt Therapeut, Charleston, SC 29425 USA
关键词
D O I
10.1016/j.biopha.2008.06.017
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
16
引用
收藏
页码:425 / 426
页数:2
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