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Guilan Univ Med Sci, Razi Hosp, Inflammatory Lung Dis Res Ctr, Inflammatory Lung Dis Res Ctr,Dept Internal Med, Sardar Jangal Ave, Rasht, Iran Guilan Univ Med Sci, Razi Hosp, Inflammatory Lung Dis Res Ctr, Inflammatory Lung Dis Res Ctr,Dept Internal Med, Sardar Jangal Ave, Rasht, Iran